ONE of the most valuable weapons in the war on malaria is artemisinin, a drug derived from the leaves of sweet wormwood. Its discovery, inspired by wormwood’s use as a herbal remedy for the disease, brought Tu Youyou, the scientist responsible for making it, the first Nobel prize for medicine awarded to a researcher working in China. Artemisinin has, though, proved stubbornly difficult to synthesise chemically, meaning that extract-of-wormwood is still the main source of supply. That is a problem, for wormwood plants take between 190 and 240 days to mature. Moreover, yields are not huge—a mere half a milligram per gram of dried wormwood leaves. Alternative sources would thus be welcome.
One is to engineer relevant genes into yeast cells. That works, but only up to a point. The commercial process based on this method turns out artemisinic acid, not artemisinin. Further chemical treatment is needed to produce the drug, and the end product has had difficulty competing with artemisinin derived from plants. However, Shashi Kumar of the International Centre for Genetic Engineering and Biotechnology, in New Delhi, is proposing a different approach, using a plant instead of a fungus. As he reports in Molecular Plant, he has engineered tobacco to make artemisinin faster and better than wormwood can.
Horizons Hosts James Dorsey for a Discussion on Middle East Escalation
The Center for International Relations and Sustainable Development (CIRSD) hosted an award-winning journalist and scholar Dr. James M. Dorsey for a special Horizons Discussion on June 23rd, 2025. In conversation with Horizons Managing Editor Stefan Antić, Dorsey unpacked the lightning-fast escalation between Israel and Iran, the Trump administration’s divided response, and the wider stakes for regional and great-power politics.
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Vuk Jeremić at St. Petersburg Economic Forum: “We Are Living in a Time of Grave Geopolitical Instability”
St. Petersburg, June 2025 – Speaking at the St. Petersburg International Economic Forum on the high-level panel “Eco-Rethinking of the Global Financial System,” Vuk Jeremić, President of the Center for International Relations and Sustainable Development (CIRSD), delivered a stark warning about the risks posed by escalating global tensions to any serious attempt at international financial system reform.
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CIRSD Hosts Ugandan Presidential Advisor Odrek Rwabwogo in Latest Horizons Discussion: A Deep Dive into Africa’s Industrial Future
The Center for International Relations and Sustainable Development (CIRSD) hosted Mr. Odrek Rwabwogo, Uganda’s Presidential Advisor on Exports and Industrial Development, as the featured guest in the latest installment of its flagship Horizons Discussion series — the main dialogue platform of Horizons journal.
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CIRSD Vice President Stefan Jovanović Speaks at Regional Conference on China’s Role in the Western Balkans
Belgrade, June 5, 2025 – Stefan Jovanović, Vice President of the Center for International Relations and Sustainable Development (CIRSD), participated in the regional conference “Democracy Meets Strategy: Parliament’s Place in China Policy”, held in Belgrade. The event gathered parliamentarians, policymakers, and experts from across the Western Balkans to examine the region’s evolving cooperation with the People’s Republic of China.
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