Picture this. It is 1966. You are standing in a government office in Washington, DC, watching a uniformed official tell a man in business attire, “Your mission is to eradicate an enemy that has killed more people than both world wars combined. You will have a paltry budget, a small team, and should you fail, the Secretary will disavow any knowledge of your actions.”
It sounds like a scene from a Hollywood movie. And, indeed, it mirrors the opening scenes of the Mission: Impossible television series that premiered that year. But it really happened, if not in precisely those words. The official was Assistant Surgeon General James Watt; the man with the mission was Communicable Disease Center (CDC) scientist Donald Henderson; and the enemy was smallpox.
The mission certainly seemed impossible. At the time, smallpox was killing as many as two million people, and infecting another 15 million, each year. Yet, like in the series, Henderson and his team at the World Health Organization defied expectations. In just over a decade, smallpox became the first – and, so far, the only – infectious human disease ever to be fully eradicated.
Horizons Discussion in Belgrade Explores Europe’s Future with Zachary Karabell
Belgrade, September 29, 2025 — The Center for International Relations and Sustainable Development (CIRSD) hosted another edition of its renowned Horizons Discussions series, featuring Zachary Karabell, prominent American author, investor, and founder of The Progress Network, in conversation with Vuk Jeremić, CIRSD President and former President of the UN General Assembly.
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Global Preventive Diplomacy Initiative Launched in New York Ahead of UNGA 80
New York, NY — The Global Preventive Diplomacy Initiative (GPDI) was launched at an exclusive event organized by the Center for International Relations and Sustainable Development (CIRSD) on the top floor of New York’s iconic MetLife Building, bringing together diplomats, philanthropists, business leaders, academics, and thought leaders for a conversation on the future of conflict prevention and international cooperation. The launch came just days before the opening of the 80th Session of the United Nations General Assembly, which annually brings together heads of state and government for the High-Level General Debate — making New York the world’s diplomatic capital.
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Eighty years after its founding, the UN finds itself at a critical juncture. Its purpose is on trial, and its mission urgently requires recalibration. The world it inherited from the scorches of the Second World War no longer exists, yet many of the organisation’s practices remain rooted in a bygone era – out of sync with today’s realities and detached from those it was created to serve.
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